North Carolina State University - Department Of Genetics

Linda  Hanley-Bowdoin
Linda Hanley-Bowdoin
Program in Genetics

People

William Neal Reynolds Professor of Biochemistry

Type: Faculty

Education:
PhD, Rockefeller University

Contact Info
Office: 360C Partners III, Centennial Campus
T: 919-515-6663
Email: Linda_Hanley-Bowdoin

Website: Visit our Lab Home Page

Research Areas: Molecular / Cell / Development

My lab has active areas of research in virus-induced gene silencing, geminivirus-host interactions, and in abiotic stress. Long-term goals are to understand how geminiviruses, which are DNA viruses that transcribe their genes in plant nuclei, interact with plant gene silencing pathways, and to be able to harness these viruses for use in the functional genomics of crop plants. A second long-term goal is to understand how modulation of intracellular levels of calcium in the endoplasmic reticulum affects root growth and stress tolerance.

Selected Publications:

Tuttle JR, Idris AM, Brown JK, Haigler CH, and Robertson D. (2008) Geminivirus-mediated Gene Silencing from Cotton Leaf Crumple Virus Is Enhanced by Low Temperature in Gossypium hirsutum. Plant Physiol 148: 41–50.

Jordan CV, Shen W, Hanley-Bowdoin L, and Robertson D. (2007) Geminivirus-induced gene silencing of the tobacco retinoblastoma-related gene results in cell death and altered development. Plant Molecular Biology. 65:163–175.

Smith CA, Woloshuk CP, Robertson D, and Payne GS. (2007) Silencing of the Aflatoxin Gene Cluster in a Diploid Strain of Aspergillus flavus is Suppressed by Ectopic aflR Expression. Genetics. 176: 2077–2086.

Blevins T, Rajeswaran R, Shivaprasad PV, Beknazariants D, Si-Ammour A, Park H-S, Vazquez F, Robertson D, Meins F, Hohn T, and Pooggin P. (2006) Four plant Dicers mediate viral small RNA biogenesis and DNA virus induced silencing. Nucleic Acids Research 34: 6233–6246.

Muangsan N, Beclin C, Turnage M, Vaucheret H, and Robertson D. (2004) Geminivirus VIGS of endogenous genes requires SGS2/SDE1 and SGS3 and defines a new branch in the genetic pathway for silencing in plants. Plant J. 38: 1004–1014.

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f: 919.515.3355
e: genetics@ncsu.edu
Program in Genetics
Box 7614
N.C. State University
Raleigh, NC 27695-7614