North Carolina State University - Program Of Genetics

John  Shorter
John Shorter
Program in Genetics


PHD Student

Type: Graduate Students

Group: Mackay Lab

BS, University of Michigan-Ann Arbor
MS, Purdue University

Contact Info
Email: JRShorte

Website: Genetics Graduate Student Association

I am interested in understanding genetic variation of complex traits. Using the Drosophila Genetic Reference Panel, I measured aggressive behaviors and identified a large network of epistatically interacting genes that affect aggression. When these genes were manipulated using RNAi knockdown or transposable element insertion, they were shown to significantly alter aggression levels. Many of these genes were not identified as significant in a GWA, highlighting the importance of understanding epistatic interaction in complex traits. I am also interested in understanding how odorant binding proteins affect behavior. I have characterized one particular odorant binding protein and observed that it is involved in mating behavior, aggression, and cuticular hydrocarbon formation. Finally, I am interested in understanding how royal jelly supplemented feeding alters development and other life history traits.

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Program in Genetics
Box 7614
N.C. State University
Raleigh, NC 27695-7614