North Carolina State University - Program Of Genetics

Natasha  Olby
Natasha Olby
Program in Genetics


Professor of Neurology and Neurosurgery

Type: Faculty

Veterinary Degree and PhD, University of Cambridge, UK
Residency, NC State University

Contact Info
Office: 346 CVM Research Building
T: 919-513-8286
Email: Natasha_Olby

Website: Visit my Homepage

Research Areas:

The mission of Dr Olby's Laboratory is to use clinical case material to identify, describe, understand and treat a wide range of neurological disorders in the dog that parallel human disorders. There is a special focus on the genetics of neurodegenerative disease and treatment of spinal cord injury. Graduate students are expected to learn about the clinical disease, including understanding how to quantify the trait in the clinical patient, from advanced imaging, and histopathology and to use that careful phenotyping to perform genomics research.

Selected Publications:

Urkasemsin G, Linder KE, Bell JS, de Lahunta A, and Olby NJ. (2012). Mapping of Purkinje Neuron Loss and Polyglucosan Body Accumulation in Hereditary Cerebellar Degeneration in Scottish Terriers. Vet Pathol. Sep;49(5):852–859.

Salzmann CA, Olivry T, Nielsen DM, Papps J, Harris TL, and Olby NJ. (2011). Genome-wide linkage study of atopic dermatitis in West Highland White Terriers. BMC Genetics. Apr 21;12:37.

Abitbol M, Thibaud JL, Olby N, Hitte C, Puech JP, Hédan B, Dréano S, Brahimi S, Uriarte A, Delattre D, Bernex F, André C, Gray F, Delisle F, Caillaud C, Panthier J-J, Aubin-Houzelstein G, Blot S, and Tiret L. (2010). A canine Arylsulfatase G (ARSG) mutation leading to a sulfatase deficiency is associated with neuronal ceroid lipofuscinosis. Proc Natl Acad Sci U S A. 107:14775–14780.

Thames RA, Robertson ID, Flegel T, Henke D, O’Brien DP, Coates JR, and Olby NJ. (2010). Brain Morphometry in Dogs using Magnetic Resonance Imaging: the Effect of Breed, Age and Cerebellar Degenerative Disease. Vet Radiol US. 51:246–253.

Urkasemsin G, Linder KE, Bell JS, de Lahunta A, and Olby NJ. (2010). Hereditary Cerebellar Degeneration in Scottish Terriers. J Vet Int Med. 24(3):565–570.

Olby NJ, Blot S, Thibaud J-L, Phillips J, O'Brien DP, Burr J, Berg J, Brown T, and Breen M. (2004). Cerebellar Cortical Degeneration in Adult American Staffordshire Terriers. J Vet Intern Med 18:201–208.

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North Carolina State University College of Sciences Intranet p: 919.515.2292
f: 919.515.3355
Program in Genetics
Box 7614
N.C. State University
Raleigh, NC 27695-7614